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IFNG_PK_B_taurus

PKB-number: PKB309
Definition: Regulatory pseudoknot of the interferon-gamma gene 5'-UTR
Organism: Bos taurus (cow)
Abbreviation: IFNG_PK_B_taurus
RNA type: mRNA
Keywords: translation; PKR
EMBL number: Z54144
Submitted by: A.P. Gultyaev (a.p.gultyaev@biology.leidenuniv.nl)
Supported by: Mutagenesis,Sequence comparison,Structure probing
References: [1] Cohen-Chalamish S. et al. (2009). Nature Chem. Biol. 5:896-903
Comment: This pseudoknot can adopt alternative conformations, conserved in mammalian IFN-gamma mRNA's [1].
Stem sizes:
Loop sizes:
6 24
0 4 5
Position Paired:
2628-2633; 2683-2688
2634-2634; 2736-2736
2637-2637; 2733-2733
2639-2641; 2728-2730
2645-2646; 2721-2722
2651-2652; 2716-2717
2657-2664; 2705-2712
2666-2666; 2703-2703
2668-2669; 2701-2702
2675-2678; 2694-2697
Bracket view of structure:
        2610      2620      2630      2640      2650      2660      2670      2680
#      6789|123456789|123456789|123456789|123456789|123456789|123456789|123456789|
$ 2606 AAGGAGACACAGUACAUUCUUCUGAUCAUCUGCAGAUCAGCAAUUAGAAAAGAAAGAUCAGCUACCUCCUUGGGA=2680
% 2606 ::::::::::::::::::::::(((((([::[:[[[:::[[::::[[::::[[[[[[[[:[:[[:::::[[[[::

             2690      2700      2710      2720      2730      2740      2750
#      123456789|123456789|123456789|123456789|123456789|123456789|123456789|
$ 2681 CCUGAUCAUAACACAGGAGCUACCGAUUUCAACUACUCCGGCCUAACUCUCUCCUAAACAAUGAAAUAUA=2750
% 2681 ::)))))):::::]]]]:::]]]:]]]]]]]]:::]]:::]]:::::]]]::]::]::::::::::::::


Contact:
© final design and maintenance: F.H.D.(Eke) van Batenburg; 2010-1-18 PKB00309.HTML